TK2 Nucleosides Treatment
Deoxypyrimidine monophosphate bypass therapy for thymidine kinase 2 deficiency
Maxwell has TK2 mitochondrial disease so is unable to breathe by himself. He’s connected to a ventilator 24/7, he can’t talk, walk or move his arms and legs this means he requires around the clock care by his parents and nursing team. There is a treatment available for Maxwell which unfortunately isn’t funded. The treatment costs £13,000 per year.
Maxwell will be the first person in the UK to go onto this treatment. We as parents will try anything to help Maxwell have a better quality of life and be happy.
The diagram gives a graphical summary of the pathways modulated by oral gavage dCMP/dTMP treatment.